反应详情

To 100 ml of toluene were added 12.0 g of 4-(2-propynyloxy)-3-methoxybenzoic acid, 9.0 g of thionyl chloride and 50 mg of DMF, and the mixture obtained was heated under reflux for 3 hours. Then, the reaction mixture was concentrated. The solid obtained was washed with hexane to obtain 11.0 g of 4-(2-propynyloxy)-3-methoxybenzoyl chloride represented by the formula.

1. customthe mixture obtained
2. temperaturewas heated
3. temperatureunder reflux for 3 hours
4. concentrationThen, the reaction mixture was concentrated
5. customThe solid obtained
6. washwas washed with hexane