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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 602136Generated: October 26, 2026

HCID 57572194, compound → N-[[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]methyl]piperidine-3-carboxamide hydrochloride

https://huagongshe.com/reaction/602136

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57572194HCID 57572194—
SolventHydrochloride methanolHCID 21893726—
ProductN-[[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]methyl]piperidine-3-carboxamide hydrochlorideHCID 67266868195.1%

Reaction Steps

1-tert-Butoxycarbonyl-N-[[2-(4-chlorophenyl)-4-methylthiazol-5-yl]methyl]piperidine-3-carboxamide (916 mg, 2.04 mmol) was dissolved in a 10% hydrogen chloride/methanol solution (20 mL) and the mixture was stirred at room temperature for 1 hour. Subsequently, the reaction mixture was concentrated and the residue was air-dried to give 769 mg (98%) of the desired compound as a colorless amorphous product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902367B2
Source datasetuspto-grants-2011_03
ORD IDord-790c99f952394bab810576749e3fa729
Source noteuspto-grants-2011_03