HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[4-(4-Fluorophenoxy)benzyloxy]piperidine → Methyl 3-[3-[[4-(4-fluorophenoxy)phenyl]methoxy]piperidin-1-yl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[4-(4-Fluorophenoxy)benzyloxy]piperidine | HCID 58992695 | — |
| Reactant | 3-Methoxycarbonylphenylboric acid | HCID 67170287 | — |
| Product | Methyl 3-[3-[[4-(4-fluorophenoxy)phenyl]methoxy]piperidin-1-yl]benzoate | HCID 58992659 | 42% |
Reaction Steps
Using 3-[4-(4-fluorophenoxy)benzyloxy]piperidine (157 mg, 0.521 mmol) and 3-(methoxycarbonyl)phenylboric acid (187 mg, 1.04 mmol), the same procedure was followed as in Example 2 to give 94.8 mg (42%) of the desired compound as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07902367B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-9fe8483d268b432081d988be7eb5d376 |
| Source note | uspto-grants-2011_03 |