HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Boc-amino)piperidine → Methyl 3-benzyloxy-5-[3-(tert-butoxycarbonylamino)piperidin-1-yl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Boc-amino)piperidine | HCID 4233041 | — |
| Reactant | Methyl 3-benzyloxy-5-(trifluoromethanesulfonyloxy)benzoate | HCID 18945283 | — |
| Product | Methyl 3-benzyloxy-5-[3-(tert-butoxycarbonylamino)piperidin-1-yl]benzoate | HCID 58992646 | 6% |
Reaction Steps
Using 3-(tert-butoxycarbonylamino)piperidine (301 mg, 1.50 mmol) and methyl 3-benzyloxy-5-(trifluoromethanesulfonyloxy)benzoate (595 mg, 1.52 mmol), the same procedure was followed as in Example 58 to give 39.7 mg (6.0%) of the desired compound as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07902367B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-8b90970646aa405ca444617ea50eabb7 |
| Source note | uspto-grants-2011_03 |