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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 602964Generated: October 30, 2026

HCID 15949507, compound → HCID 57666161, compound

https://huagongshe.com/reaction/602964

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 15949507HCID 15949507—
ReactantHCID 57462502HCID 57462502—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 57666161HCID 57666161—

Reaction Steps

A solution of [(1S,2R,5S)-5-[2-cyclopropyl-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl]-2-(2,4,5-trifluorophenyl)cyclohexyl]amine described in Example 2 (30.0 mg) in methanol (6 mL) was stirred with 10% palladium on carbon (6 mg) for seven days and the resulting product was purified by preparative TLC (silica, 7:93 methanol/dichloromethane) to give the title compound. LC-MS 387.3 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07906649B2
Source datasetuspto-grants-2011_03
ORD IDord-cc6b6c7e027c410488572c49e491642b
Source noteuspto-grants-2011_03