Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → N-(3,4-dichlorophenyl)-4-pyrrolidin-3-ylpiperazine-1-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | Tert-butyl 3-(4-{[(3,4-dichlorophenyl)amino]carbonyl}piperazin-1-yl)pyrrolidine-1-carboxylate | HCID 57656740 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-(3,4-dichlorophenyl)-4-pyrrolidin-3-ylpiperazine-1-carboxamide | HCID 57656838 | — |
반응 단계
tert-butyl 3-(4-{[(3,4-dichlorophenyl)amino]carbonyl}piperazin-1-yl)pyrrolidine-1-carboxylate (690 mg, 1.6 mmol) was dissolved in dichloromethane (50 ml) at room temperature. Trifluoroacetic acid (3 ml) was added and the mixture left to stir for 2 hours then concentrated in vacuo.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07906645B2 |
| 출처 데이터셋 | uspto-grants-2011_03 |
| ORD ID | ord-91f909c34aee4e5daff34aa17a9f94b8 |
| 출처 메모 | uspto-grants-2011_03 |