HCID 57952154, compound → HCID 57952160, compound

HRID 603357Notes

Reaction equation

HRID 603357 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[N:9]1[C:17]2[C:12]([CH2:13][CH:14]([CH2:18][CH3:19])[CH2:15][CH:16]=2)=[CH:11][C:10]1=[O:20]>[Pd].C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[N:9]1[C:17]2[C:12](=[CH:13][C:14]([CH2:18][CH3:19])=[CH:15][CH:16]=2)[CH2:11][C:10]1=[O:20]

Participants

4

Reactant 1

HCID 57952154HCID 57952154, compound

Product 1

HCID 57952160HCID 57952160, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 7237O-XyleneSolvent

Procedure

1-(2-Chloro-6-methyl-phenyl)-5-ethyl-1,4,5,6-tetrahydro-indol-2-one can be oxidized by classical methods, e.g. with 10% Pd—C in refluxing xylene to yield N-(2-Chloro-6-methyl-phenyl)-5-ethyl-oxindole.

Sources & evidence

ORD record
ord-7e70b68e3c114f3b98a4c9df6524a2a2
Source dataset
uspto-grants-2011_03
Patent number
US07906677B2

Reaction notes

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