HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichloro-5-fluoropyrimidine → N2,N4-bis(indol-6-yl)-5-fluoro-2,4-pyrimidinediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichloro-5-fluoropyrimidine | HCID 250705 | — |
| Reactant | 6-Aminoindole | HCID 256096 | — |
| Product | N2,N4-bis(indol-6-yl)-5-fluoro-2,4-pyrimidinediamine | HCID 11552202 | — |
Reaction Steps
In like manner to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, 2,4-dichloro-5-fluoropyrimidine and 6-aminoindole were reacted to yield N2,N4-bis(indol-6-yl)-5-fluoro-2,4-pyrimidinediamine. LCMS: ret. time: 22.39 min.; purity: 85%; MS (m/e): 359 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07906644B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-a96749cdaad9426bb4b7f79f5dcc3631 |
| Source note | uspto-grants-2011_03 |