反应详情

温度

100 °C

A mixture of 5-iodopyridin-2-amine (25.5 g), 4-methylbenzene-1-sulfonyl chloride (23.2 g) and pyridine (250 mL) was stirred at 100° C. overnight. The reaction mixture was poured into water (1.2 L) and stirred. The resulting solid was collected by filtration. The obtained solid was washed with water and diethyl ether and dried in vacuo to give the title compound (37.4 g) as a white solid.

1. stirringstirred
2. filtrationThe resulting solid was collected by filtration
3. washThe obtained solid was washed with water and diethyl ether
4. customdried in vacuo