HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloroaniline → HCID 178451334, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | Tert-butyl 2-(4-formylphenoxy)acetate | HCID 639902 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 178451334 | HCID 178451334 | — |
Reaction Steps
tert-Butyl (4-formylphenoxy)acetate (17.4 g, 73.4 mmol) was dissolved in dry toluene (120 mL) and 4-chloroaniline (9.37 g, 73.4 mmol) was added. The mixture was refluxed in a Dean-Stark apparatus for 20 hours, cooled and concentrated under reduced pressure. Hexane was added and a precipitate formed. This precipitate was filtered, washed twice with cold hexane and dried. This afforded the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07906502B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-5e5f44a9d724402a94fe448885cb0c7b |
| Source note | uspto-grants-2011_03 |