反应详情

A solution of 1-(tert-butoxyl carbonyl)-3-pyrrolidone (4.10 g) and N,N-dimethylformamide dimethyl acetal (30.0 mL) was heated to 140° C. for 1 h. The resulting mixture was cooled to room temperature and concentrated under reduced pressure. The residue was redissolved in a minimum amount of dichloromethane and triturated with hexane to yield a yellow precipitate. LC-MS=241.1 (M+1).

1. concentrationconcentrated under reduced pressure
2. dissolutionThe residue was redissolved in a minimum amount of dichloromethane
3. customtriturated with hexane
4. customto yield a yellow precipitate