HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanecarbonyl chloride → Cyclopr-opanecarboxylic acid (5-furan-3-yl-4-phenyl-thiazol-2-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanecarbonyl chloride | HCID 77637 | — |
| Reactant | 5-Furan-3-yl-4-phenyl-thiazol-2-ylamine | HCID 57709610 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Cyclopr-opanecarboxylic acid (5-furan-3-yl-4-phenyl-thiazol-2-yl)-amide | HCID 11493318 | — |
Reaction Steps
100 μL of a 0.3M stock solution of 5-furan-3-yl-4-phenyl-thiazol-2-ylamine and 120 μL of a 0.3M stock solution of pyridine were mixed with 120 μL of a 0.3M stock solution of cyclopropanecarbonyl chloride. The reaction mixture was shaken overnight at ambient temperature. Purification was performed by preparative LC-MS.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07910613B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-f674dbf0c5a04b2a85c121fbb8414df3 |
| Source note | uspto-grants-2011_03 |