Cyclopropanecarbonyl chloride → Cyclopropanecarboxylic acid [5-(3-methyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-thiazol-2-yl]-amide

HRID 604499Notes

Reaction equation

HRID 604499 reaction equation
[CH3:1][C:2]1[N:6]=[C:5]([C:7]2[S:11][C:10]([NH2:12])=[N:9][C:8]=2[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[O:4][N:3]=1.[CH:19]1([C:22](Cl)=[O:23])[CH2:21][CH2:20]1>>[CH3:1][C:2]1[N:6]=[C:5]([C:7]2[S:11][C:10]([NH:12][C:22]([CH:19]3[CH2:21][CH2:20]3)=[O:23])=[N:9][C:8]=2[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[O:4][N:3]=1

Participants

3

Reactant 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 577095965-(3-Methyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-thiazol-2-ylamine

Product 1

HCID 11609536Cyclopropanecarboxylic acid [5-(3-methyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-thiazol-2-yl]-amide

Procedure

Prepared from 5-(3-methyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-thiazol-2-ylamine and cyclopropanecarbonyl chloride.

Sources & evidence

ORD record
ord-e3ca9be15ba84f10aa8783d3a9459fd1
Source dataset
uspto-grants-2011_03
Patent number
US07910613B2

Reaction notes

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