Fumaric Acid → 1192731-63-7

Participants

Reaction Steps

Fumaric acid (94.9 mg, 0.82 mmol) was added to a solution of (2R)-2-amino-2-methyl-4-{1-methyl-5-[4-(4-methylphenyl)butanoyl]pyrrol-2-yl}butan-1-ol (560 mg, 1.6 mmol) obtained in Example 1 (1b) in ethanol (18 mL) at room temperature and the mixture was left to stand for 15 hours. The precipitated crystal was collected by filtration to obtain the title compound (622.7 mg, yield: 95%).

Provenance & Evidence