Methyl iodide → (1-Ethylpyrrol-2-yl)methyltrimethylammonium iodide

Participants

Reaction Steps

Methyl iodide (7.7 mL, 124 mmol) was added to a solution of 2-(N,N-dimethylaminomethyl)-1-ethylpyrrol (15.6 g, 102 mmol) in ethanol (150 mL) under ice-cooling and the mixture was stirred at room temperature for 3 hours. Ethyl acetate (150 mL) was added to the reaction mixture and the precipitated crystal was collected by filtration. After the crystal was washed with ethyl acetate and dried to obtain (1-ethylpyrrol-2-yl)methyltrimethylammonium iodide (20.0 g, yield: 66%).

Provenance & Evidence