Ethylbenzene → 2-(4-Ethylbenzyl)-4-bromo-1-chlorobenzene
Reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([Cl:11])=[C:6]([CH:10]=1)[C:7](O)=O.[CH2:12]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH3:13]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([Cl:11])=[C:6]([CH2:7][C:17]2[CH:18]=[CH:19][C:14]([CH2:12][CH3:13])=[CH:15][CH:16]=2)[CH:10]=1Participants
3
Procedure
Synthesis was performed by a similar method as in Preparation Example 14 using 5-bromo-2-chlorobenzoic acid and ethylbenzene.
Workup
- customSynthesis
Sources & evidence
- ORD record
- ord-d687ff5485274e4791e166e0ea8e331f
- Source dataset
- uspto-grants-2011_03
- Patent number
- US07910619B2
Reaction notes
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