Dimethylformamide dimethyl acetal → HCID 72566760, compound

HRID 604846Notes

Reaction equation

HRID 604846 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]([P:10]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:7]=[CH:8][CH:9]=1)(=[O:3])[CH3:2].CO[CH:25](OC)[N:26]([CH3:28])[CH3:27]>>[CH3:25][N:26]([CH3:28])[CH:27]=[CH:2][C:1]([C:4]1[CH:5]=[C:6]([P:10]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:7]=[CH:8][CH:9]=1)=[O:3]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 59804969HCID 59804969, compound

Product 1

HCID 72566760HCID 72566760, compound

Procedure

A mixture of 9.9 g (32.6 mmol) of (3-acetylphenyl)diphenyl phosphane and 7.7 g (64.7 mmol) of N,N-dimethylformamide dimethylacetal is refluxed under cover gas for 2 h. After removal of the volatiles in high vacuum, the product crystallizes at room temperature. The orange solid is washed with diethyl ether. (Purity: >95%)

Workup

  1. temperatureis refluxed under cover gas for 2 h
  2. customAfter removal of the volatiles in high vacuum
  3. customthe product crystallizes at room temperature
  4. washThe orange solid is washed with diethyl ether

Sources & evidence

ORD record
ord-0f865afd148044ebad9d1f7c8703ebbb
Source dataset
uspto-grants-2011_03
Patent number
US07910744B2

Reaction notes

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