Hydrazine hydrate (1:1) → HCID 178420540, compound

HRID 604847Notes

Reaction equation

HRID 604847 reaction equation
CN(C)[CH:3]=[CH:4][C:5]([C:7]1[CH:8]=[C:9]([P:13]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:10]=[CH:11][CH:12]=1)=O.O.[NH2:28][NH2:29]>C(O)C>[NH:28]1[CH:3]=[CH:4][C:5]([C:7]2[CH:8]=[C:9]([P:13]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:10]=[CH:11][CH:12]=2)=[N:29]1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 72566760HCID 72566760, compound

Product 1

HCID 178420540HCID 178420540, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 1.8 g (5.1 mmol) of [3-(3-dimethylamino-1-oxoprop-2-en-yl)phenyl]diphenyl phosphane and 2.6 g (51 mmol) hydrazine monohydrate in 20 ml of ethanol is heated to boil under cover gas for 3 h. After cooling of the solution to room temperature, the solvent is removed in a vacuum. The remaining colorless oily residue is recrystallized from acetic acid ethyl ester. A colorless solid is obtained (yield: >70%).

Workup

  1. customthe solvent is removed in a vacuum
  2. customThe remaining colorless oily residue is recrystallized from acetic acid ethyl ester
  3. customA colorless solid is obtained (yield: >70%)

Sources & evidence

ORD record
ord-fe5205de80734e348ac500c2dbd9b51c
Source dataset
uspto-grants-2011_03
Patent number
US07910744B2

Reaction notes

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