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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 605016Generated: October 30, 2026

Trifluoroacetic acid → HCID 178489120, compound

https://huagongshe.com/reaction/605016

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 178489119HCID 178489119—
SolventMethanolHCID 887—
ProductHCID 178489120HCID 178489120—

Reaction Steps

2-[4-({4-[5-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl]piperidin-1-yl}methyl)phenyl]-3-phenyl-1,6-naphthyridin-5(6H)-one (300 mg, 0.53 mmol) was dissolved in MeOH and TFA (40 μL, 0.53 mmol) was added. The solvent was evaporated under reduced pressure and the yellow residue was dried under high vacuum for 16 h to give 2-[4-({4-[5-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl]piperidin-1-yl}methyl)phenyl]-3-phenyl-1,6-naphthyridin-5(6H)-one trifluoroacetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07910561B2
Source datasetuspto-grants-2011_03
ORD IDord-60ec76d8a8b1467d985d336bb673b1e1
Source noteuspto-grants-2011_03