HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 178489120, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 178489119 | HCID 178489119 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178489120 | HCID 178489120 | — |
Reaction Steps
2-[4-({4-[5-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl]piperidin-1-yl}methyl)phenyl]-3-phenyl-1,6-naphthyridin-5(6H)-one (300 mg, 0.53 mmol) was dissolved in MeOH and TFA (40 μL, 0.53 mmol) was added. The solvent was evaporated under reduced pressure and the yellow residue was dried under high vacuum for 16 h to give 2-[4-({4-[5-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl]piperidin-1-yl}methyl)phenyl]-3-phenyl-1,6-naphthyridin-5(6H)-one trifluoroacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07910561B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-60ec76d8a8b1467d985d336bb673b1e1 |
| Source note | uspto-grants-2011_03 |