4-Chloro-3-nitrobenzoyl chloride → N-(2-Bromo-benzyl)-4-chloro-3-nitro-benzamide

HRID 605079Notes

Reaction equation

[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12].[Br:14][C:15]1[CH:22]=[CH:21][CH:20]=[CH:19][C:16]=1[CH2:17][NH2:18]>>[Br:14][C:15]1[CH:22]=[CH:21][CH:20]=[CH:19][C:16]=1[CH2:17][NH:18][C:6](=[O:7])[C:5]1[CH:9]=[CH:10][C:2]([Cl:1])=[C:3]([N+:11]([O-:13])=[O:12])[CH:4]=1

Participants

Reactant 2

HCID 1234774-Chloro-3-nitrobenzoyl chloride

HCID 3340722-Bromobenzylamine

Product 1

HCID 60737171N-(2-Bromo-benzyl)-4-chloro-3-nitro-benzamide

Procedure

A mixture of 4-chloro-3-nitrobenzoyl chloride was reacted with 2-Bromo-benzylamine to produce N-(2-Bromo-benzyl)-4-chloro-3-nitro-benzamide according to the procedure of Example 10A, which was treated sequentially using the procedures from Examples 22A and 22B to provide the title product.

Sources & evidence

ORD record: ord-a2c37de9ab2e4c98b93ac3c11efab2cd
Source dataset: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07910595B2

Reaction notes

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