Ammonium Chloride → HCID 67040392, compound

HRID 605193Notes

Reaction equation

HRID 605193 reaction equation
[Cl:1][C:2]([Cl:36])([Cl:35])[CH2:3][O:4][C:5](=[O:34])[NH:6][C:7]1[CH:12]=[CH:11][C:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([C:20](=[O:30])[N:21]([C:23]3[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=3)[CH3:22])=[CH:16][C:15]=2[N+:31]([O-])=O)=[CH:9][CH:8]=1.[NH4+].[Cl-]>[Fe]>[Cl:35][C:2]([Cl:1])([Cl:36])[CH2:3][O:4][C:5](=[O:34])[NH:6][C:7]1[CH:12]=[CH:11][C:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([C:20](=[O:30])[N:21]([C:23]3[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=3)[CH3:22])=[CH:16][C:15]=2[NH2:31])=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 67040200HCID 67040200, compound

Product 1

HCID 67040392HCID 67040392, compoundYield 73.2%

Reagents, catalysts & solvents 1

HCID 23925IronCatalyst

Procedure

The product from Example 165A (295 mg, 0.516 mmol) was reduced with Fe and NH4Cl following the procedure from Example 9E to yield the title compound (205 mg, 73% yield)

Sources & evidence

ORD record
ord-6b8e4e3d56874c2295ed3923e65ad732
Source dataset
uspto-grants-2011_03
Patent number
US07910595B2

Reaction notes

Loading…