Water → HCID 67040926, compound

Participants

Reaction Steps

The title compound was prepared by dissolving 4-Trifluoromethyl-phenylamine (475 mg, 2.95 mmol) in THF (20 ml) at room temperature. To this solution was added Hunig's base (762 mg, 5.86 mmol) and then a solution of the product from Example 172a (600 mg, 2.95 mmol) in THF (10 mL) was added drop wise over 5 minutes. After complete addition the reaction mixture was allowed to stir at room temperature for 1 hr and was poured into water and the title compound collected by filtration (900 mg, 93%).

Provenance & Evidence