Ammonium Chloride → HCID 67040934, compound

HRID 605222Notes

Reaction equation

HRID 605222 reaction equation
[Cl:1][C:2]([Cl:37])([Cl:36])[CH2:3][O:4][C:5](=[O:35])[NH:6][C:7]1[CH:12]=[CH:11][C:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([C:20](=[O:31])[NH:21][C:22]3[C:27]([CH3:28])=[CH:26][C:25]([Br:29])=[CH:24][C:23]=3[CH3:30])=[CH:16][C:15]=2[N+:32]([O-])=O)=[CH:9][CH:8]=1.[NH4+].[Cl-]>[Fe]>[Cl:36][C:2]([Cl:1])([Cl:37])[CH2:3][O:4][C:5](=[O:35])[NH:6][C:7]1[CH:12]=[CH:11][C:10]([S:13][C:14]2[CH:19]=[CH:18][C:17]([C:20](=[O:31])[NH:21][C:22]3[C:27]([CH3:28])=[CH:26][C:25]([Br:29])=[CH:24][C:23]=3[CH3:30])=[CH:16][C:15]=2[NH2:32])=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 67040132HCID 67040132, compound

Product 1

HCID 67040934HCID 67040934, compoundYield 62.4%

Reagents, catalysts & solvents 1

HCID 23925IronCatalyst

Procedure

The product from Example 207A (0.6197 mmol) was reduced with Fe and NH4Cl following the procedure from Example 9E to yield the title compound (239 mg, 62% yield) as a white solid.

Sources & evidence

ORD record
ord-b7c59205227d40eeb8541052698e114b
Source dataset
uspto-grants-2011_03
Patent number
US07910595B2

Reaction notes

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