HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 2649530, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-Fluoro-3-nitroaniline | HCID 67768 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 5-Bromothiophene-2-carbonyl chloride | HCID 605712 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 2649530 | HCID 2649530 | — |
Reaction Steps
The product from Example 241a (2.178 g, 10.25 mmol) was reacted with 4-fluoro-3-nitro-phenylamine (1.60 g, 10.25 mmol) dissolved in THF (25 mL) and Hunig's base (2.484 g, 19.22 mmol). Reaction mixture was stirred at room temperature for 1 hr at which time water was added and the title compound was collected by filtration (2.00 g, 78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07910595B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-0427ecdeff674ac291c94d538c3bce14 |
| Source note | uspto-grants-2011_03 |