Ammonium Chloride → HCID 67040952, compound

HRID 605259Notes

Reaction equation

HRID 605259 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11][C:12]2[CH:17]=[CH:16][C:15]([NH:18][C:19](=[O:30])[C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([C:26]([F:29])([F:28])[F:27])[CH:21]=3)=[CH:14][C:13]=2[N+:31]([O-])=O)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[NH4+].[Cl-]>[Fe]>[NH2:31][C:13]1[CH:14]=[C:15]([NH:18][C:19](=[O:30])[C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([C:26]([F:29])([F:27])[F:28])[CH:21]=2)[CH:16]=[CH:17][C:12]=1[S:11][C:8]1[CH:9]=[CH:10][C:5]([C:1]([CH3:3])([CH3:4])[CH3:2])=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 67040858HCID 67040858, compound

Product 1

HCID 67040952HCID 67040952, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 23925IronCatalyst

Procedure

The product from Example 242b was reduced with Fe and NH4Cl following the procedure from Example 9E to give the title compound (206 mg, 70%).

Sources & evidence

ORD record
ord-03b4c1cd6a02466a871846d897aab4f1
Source dataset
uspto-grants-2011_03
Patent number
US07910595B2

Reaction notes

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