HRID605408

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)Nc1ccc(Sc2ccc(C(=O)O)cc2Nc2ncnc3nc(C(C)C)ccc23)cc1

HCID67040871

未命名化合物

结构：CC(C)(C)OP(=O)(OCC(C)(N)c1ccccc1)OC(C)(C)C

HCID67041033

未命名化合物

PRODUCTS

生成物

结构：COC(=O)Nc1ccc(Sc2ccc(C(=O)NC(C)(COP(=O)(OC(C)(C)C)OC(C)(C)C)c3ccccc3)cc2Nc2ncnc3nc(C(C)C)ccc23)cc1

HCID67040468

未命名化合物

收率 43%

PROCEDURE

实验过程

The title compound was prepared (yield 43%) by the procedure of Example 441E substituting the product of Example 442C for the product of Example 441D.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3c2bdd458e9648ec8332772e7d5f6a5c
来源数据集: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07910595B2
来源说明: uspto-grants-2011_03

反应 SMILES

[P:1]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])([O:3][CH2:4][C:5]([NH2:13])([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:6])=[O:2].[CH:24]([C:27]1[CH:28]=[CH:29][C:30]2[C:35]([NH:36][C:37]3[CH:38]=[C:39]([CH:43]=[CH:44][C:45]=3[S:46][C:47]3[CH:52]=[CH:51][C:50]([NH:53][C:54]([O:56][CH3:57])=[O:55])=[CH:49][CH:48]=3)[C:40](O)=[O:41])=[N:34][CH:33]=[N:32][C:31]=2[N:58]=1)([CH3:26])[CH3:25]>>[C:20]([O:19][P:1]([O:3][CH2:4][C:5]([NH:13][C:40]([C:39]1[CH:43]=[CH:44][C:45]([S:46][C:47]2[CH:48]=[CH:49][C:50]([NH:53][C:54](=[O:55])[O:56][CH3:57])=[CH:51][CH:52]=2)=[C:37]([NH:36][C:35]2[C:30]3[CH:29]=[CH:28][C:27]([CH:24]([CH3:26])[CH3:25])=[N:58][C:31]=3[N:32]=[CH:33][N:34]=2)[CH:38]=1)=[O:41])([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:6])([O:14][C:15]([CH3:16])([CH3:18])[CH3:17])=[O:2])([CH3:23])([CH3:22])[CH3:21]