HCID 67040380, compound → HCID 67041190, compound

Participants

Reaction Steps

The title compound was prepared (yield 71%) by the procedure of Example 385G substituting the product of Example 448B for the product of Example 385F. 1H-NMR (300 MHz, DMSO-d6) δ ppm: 1.34 (d, J=7.0 Hz, 6H), 3.23 (septet, J=7.0 Hz, 1H), 4.48-4.79 (m, 2H), 5.32-5.49 (m, 1H), 6.62 (d, J=8.5 Hz, 2H), 6.86 (d, J=8.4 Hz, 1H), 7.13 (d, J=8.5 Hz, 2H), 7.28 (t, J=7.0 Hz, 1H), 7.35 (t, J=7.0 Hz, 2H), 7.43 (d, J=7.0 Hz, 2H), 7.68 (d, J=8.1 Hz, 1H), 7.73 (br-d, J=8.4 Hz, 1H), 7.88 (br-s, 1H), 8.61 (br-s, 1H), 8.89 (d, J=8.1 Hz, 1H), 9.00 (d, J=8.1 Hz, 1H), 10.45 (br-s, 1H) MS ESI+ m/z: 553 (M+H), ESI− m/z: 551 (M+H).

Provenance & Evidence