反应详情

A mixture of methyl 5-methyl-2-(pyridin-4-yl)benzoate (8.8 g), 6 N hydrochloric acid (65 mL) and acetic acid (100 mL) was heated under reflux overnight. The solvent was evaporated under reduced pressure, and the obtained solid was washed with ethyl acetate to give the title compound (6.6 g).

1. temperaturewas heated
2. temperatureunder reflux overnight
3. customThe solvent was evaporated under reduced pressure
4. washthe obtained solid was washed with ethyl acetate