Ammonium Hydroxide → HCID 2798152, compound

HRID 606274Notes

Reaction equation

HRID 606274 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([S:20](Cl)(=[O:22])=[O:21])[CH:5]=[C:6]([Cl:19])[C:7]=1[O:8][C:9]1[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][C:10]=1[Cl:18].[OH-].[NH4+:25]>ClCCl>[Cl:1][C:2]1[CH:3]=[C:4]([S:20]([NH2:25])(=[O:22])=[O:21])[CH:5]=[C:6]([Cl:19])[C:7]=1[O:8][C:9]1[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][C:10]=1[Cl:18]

Participants

4

Reactant 2

HCID 14923Ammonium HydroxideHCID 27743613,5-Dichloro-4-(2-chloro-4-nitrophenoxy)benzene-1-sulfonyl chloride

Product 1

HCID 2798152HCID 2798152, compoundYield 94%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2 m. moles of 3,5-Dichloro-4-(2-Chloro-4-Nitrophenoxy)Benzene-1-Sulfonyl Chloride (932 mg) in 5 ml of dichloromethane was cooled to −78° C. and 2 ml of ammonium hydroxide solution added to it. The reaction was stirred for 4 hours. The solvent was evaporated to give 755 mg (94% yield) of pure 3,5-dichloro-4-(2-chloro-4-nitro phenoxy) benzenesulfonamide.

Workup

  1. customThe solvent was evaporated

Sources & evidence

ORD record
ord-d137ab78b83943fcade4dbefe0a262ff
Source dataset
uspto-grants-2011_03
Patent number
US07915293B2

Reaction notes

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