HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,8-Difluoro-2H-chromene → 8-Bromo-6-fluoro-2H-chromene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,8-Difluoro-2H-chromene | HCID 22482814 | — |
| Reactant | 2-Bromo-4-fluoro-1-prop-2-ynyloxybenzene | HCID 22482868 | — |
| Product | 8-Bromo-6-fluoro-2H-chromene | HCID 22482798 | 47% |
Reaction Steps
This compound was prepared analogously to 5,8-difluoro-2H-chromene but using (15 g, 65 mmol) of 2-bromo-4-fluoro-1-prop-2-ynyloxybenzene to give the title compound (7 g, 46%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915295B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-c60f706f8c1e435cadfbca877e9ceedd |
| Source note | uspto-grants-2011_03 |