HCID 178468933, compound → HCID 178524389, compound

Participants

Reaction Steps

By a method similar to that in Example 42 and using, instead of ethyl 4-[({[4-oxo-2-({[(2-{[3-(1H-1,2,4-triazol-3-yl)propyl]oxy}pyridin-4-yl)methyl]amino}carbonyl)-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl]methyl}oxy)methyl]benzoate, ethyl 4-({[4-oxo-2-({3-[2-(1H-1,2,4-triazol-3-yloxy)ethoxy]benzyl}carbamoyl)-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl]methoxy}methyl)benzoate obtained in Example 49, the title compound was obtained as a white powder (419.2 mg, 80%).

Provenance & Evidence