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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 606409Generated: October 29, 2026

HCID 59298535, compound → HCID 178522986, compound

https://huagongshe.com/reaction/606409

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59298535HCID 59298535—
Reactant1-[2-({3-[1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]propyl}oxy)pyridin-4-yl]methanamineHCID 66768769—
Reactant1-{3-[(2-([1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]oxy)ethyl)oxy}phenyl]methanamineHCID 66769099—
ReactantEthyl 4-oxo-3,4-dihydroquinazoline-2-carboxylateHCID 135437466—
ProductHCID 178522986HCID 178522986—

Reaction Steps

By a method similar to that in Example 22, and using, instead of ethyl 4-oxo-3,4-dihydro-2-quinazolinecarboxylate, ethyl 4-oxo-5-pyridin-4-yl-3,4-dihydrothieno[2,3-d]pyrimidine-2-carboxylate obtained in Reference Example 66 and using, instead of 1-[2-({3-[1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]propyl}oxy)pyridin-4-yl]methaneamine, 1-{3-[(2-{[1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]oxy}ethyl)oxy]phenyl}methanamine obtained in Reference Example 32, the title compound was obtained as a white powder (142.0 mg, 59%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07915267B2
Source datasetuspto-grants-2011_03
ORD IDord-b24e8eb6123d4a39acef4bbf88990bc3
Source noteuspto-grants-2011_03