Ethyl 4-[3-({[(5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)carbonyl]amino}methyl)phenoxy]butanoate → 4-[3-({[(5-Methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)carbonyl]amino}methyl)phenoxy]butanoic acid

Participants

Reaction Steps

By a method similar to that in Example 42 and using, instead of ethyl 4-[({[4-oxo-2-({[(2-{[3-(1H-1,2,4-triazol-3-yl)propyl]oxy}pyridin-4-yl)methyl]amino}carbonyl)-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl]methyl}oxy)methyl]benzoate, ethyl 4-[3-({[(5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)carbonyl]amino}methyl)phenoxy]butanoate obtained in Reference Example 122, the title compound was obtained as a white powder (465.7 mg, 91%).

Provenance & Evidence