HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59298384, compound → HCID 178522976, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59298384 | HCID 59298384 | — |
| Reactant | 1-[2-({3-[1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]propyl}oxy)pyridin-4-yl]methanamine | HCID 66768769 | — |
| Reactant | 1-{3-[(2-([1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]oxy)ethyl)oxy}phenyl]methanamine | HCID 66769099 | — |
| Reactant | Ethyl 4-oxo-3,4-dihydroquinazoline-2-carboxylate | HCID 135437466 | — |
| Product | HCID 178522976 | HCID 178522976 | — |
Reaction Steps
By a method similar to that in Example 22, and using, instead of ethyl 4-oxo-3,4-dihydro-2-quinazolinecarboxylate, ethyl 5-biphenyl-4-yl-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-2-carboxylate obtained in Reference Example 136 and using, instead of 1-[2-({3-[1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]propyl}oxy)pyridin-4-yl]methaneamine, 1-{3-[(2-{[1-(triphenylmethyl)-1H-1,2,4-triazol-3-yl]oxy}ethyl)oxy]phenyl}methanamine obtained in Reference Example 32, the title compound was obtained as a white powder (155.4 mg, 85%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915267B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-0b27fdd206594ba0a5fa2c89aa84479d |
| Source note | uspto-grants-2011_03 |