HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 3-[3-(1H-imidazol-1-yl)propoxy]benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | 3-(2-Chloroethoxy)benzonitrile | HCID 13569167 | — |
| Reactant | 3-(3-Chloropropoxy)benzonitrile | HCID 21994081 | — |
| Reactant | HCID 178527894 | HCID 178527894 | — |
| Product | 3-[3-(1H-imidazol-1-yl)propoxy]benzonitrile | HCID 43289180 | — |
Reaction Steps
By a method similar to that in Reference Example 2, and using, instead of 3-[(2-chloroethyl)oxy]benzonitrile, 3-[(3-chloropropyl)oxy]benzonitrile obtained in Reference Example 4 and using, instead of 1H-1,2,4-triazole-3-thiol, 1H-imidazole, the title compound was obtained as a colorless oil (1.65 g, 71%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915267B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-615527a5fbb4400b9ea48939d0d7afea |
| Source note | uspto-grants-2011_03 |