3-Methyl-4-(5-morpholin-4-ylmethyl-furan-2-yl)-benzoic acid methyl ester → 3-Methyl-4-(5-morpholin-4-ylmethyl-furan-2-yl)-benzoic acid

Participants

Reaction Steps

This ester (0.51 mmol) was heated to 70° C. in 18% HCl for 2 h at which point HPLC showed all the starting material to have been hydrolysed. The reaction was cooled and the product that precipitated out of solution was collected by filtration as a white solid. With no further purification this was coupled using the standard procedure.

Provenance & Evidence