反应详情

This ester (0.51 mmol) was heated to 70° C. in 18% HCl for 2 h at which point HPLC showed all the starting material to have been hydrolysed. The reaction was cooled and the product that precipitated out of solution was collected by filtration as a white solid. With no further purification this was coupled using the standard procedure.

1. temperatureThe reaction was cooled
2. customthe product that precipitated out of solution
3. filtrationwas collected by filtration as a white solid
4. customWith no further purification