HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Iodopyridine → 3-(3,4-Difluorophenylethynyl)-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Iodopyridine | HCID 70714 | — |
| Reactant | 3,4-Difluorophenylacetylene | HCID 13878454 | — |
| Product | 3-(3,4-Difluorophenylethynyl)-pyridine | HCID 67047622 | 21% |
Reaction Steps
Prepare essentially as described in EXAMPLE 46 using 3-iodopyridine (445 mg, 2.17 mmol) and 4-ethynyl-1,2-difluorobenzene, (prepared essentially as described in PREPARATION 14), (300 mg, 2.17 mmol) to give the title compound (87.6 mg, 21%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915424B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-27867171597e4d74b16c6691679ff754 |
| Source note | uspto-grants-2011_03 |