HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Iodobenzonitrile → 3-(5-Methoxypyridin-3-ylethynyl)-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Iodobenzonitrile | HCID 144341 | — |
| Reactant | 3-Ethynyl-5-methoxypyridine | HCID 21097349 | — |
| Product | 3-(5-Methoxypyridin-3-ylethynyl)-benzonitrile | HCID 67047710 | 68% |
Reaction Steps
Prepare essentially as described in PREPARATION 10 using 3-iodobenzonitrile (681 mg, 3.0 mmol) and 3-ethynyl-5-methoxypyridine from PREPARATION 10 (415 mg, 3.1 mmol) at room temperature for 16 h to give the title compound (564 mg, 68%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915424B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-6756eadffaa94dacad88be5fc93406fc |
| Source note | uspto-grants-2011_03 |