HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-ethynyl-3-nitro- → 5-(3-Nitrophenylethynyl)-nicotinonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-ethynyl-3-nitro- | HCID 76432 | — |
| Reactant | 5-Bromonicotinonitrile | HCID 736793 | — |
| Product | 5-(3-Nitrophenylethynyl)-nicotinonitrile | HCID 67047684 | 65% |
Reaction Steps
Prepare essentially as described in PREPARATION 10 using 5-bromonicotinonitrile (400 mg, 2.19 mmol) and 1-ethynyl-3-nitrobenzene, (prepared as described in PREPARATION 11), (644 mg, 4.38 mmol) to give the title compound (118 mg, 65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915424B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-356cc2dc00924a26a34321e8a6467ac0 |
| Source note | uspto-grants-2011_03 |