HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanone, 1-(3-iodophenyl)- → 5-(3-Acetylphenylethynyl)-nicotinonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanone, 1-(3-iodophenyl)- | HCID 84449 | — |
| Reactant | 5-[2-(Trimethylsilyl)ethynyl]pyridine-3-carbonitrile | HCID 16115699 | — |
| Product | 5-(3-Acetylphenylethynyl)-nicotinonitrile | HCID 67047791 | 49% |
Reaction Steps
Prepare according to the general procedure outlined in EXAMPLE 72 using 3′-iodoacetophenone (1.29 g, 5.24 mmol) and 5-trimethylsilanylethynyl-nicotinonitrile (1.0 g, 5.0 mmol), (prepared as described in PREPARATION 3), to give the title compound (600 mg, 49%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915424B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-65e66405b9ed4a0ead069f51d7e3ef89 |
| Source note | uspto-grants-2011_03 |