HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1-(5-Phenylethynyl-pyridin-3-yl)-ethanone O-methyloxime hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | O-Methylhydroxylamine hydrochloride | HCID 521874 | — |
| Reactant | HCID 67047758 | HCID 67047758 | — |
| Product | 1-(5-Phenylethynyl-pyridin-3-yl)-ethanone O-methyloxime hydrochloride | HCID 86622470 | 38.2% |
Reaction Steps
Prepare essentially as described in EXAMPLE 6 using methoxylamine hydrochloride (700 mg, 8.4 mmol), 1-(5-phenylethynylpyridin-3-yl)-ethanone, (prepared as described in EXAMPLE 84), (230 mg, 1.05 mmol) and potassium carbonate (720 mg, 5.24 mmol) to give the title compound (115 mg, 38%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915424B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-1676f634ca404fd48870c77a47e04cfe |
| Source note | uspto-grants-2011_03 |