HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Bromo-5-(4-fluorophenylethynyl)-pyridine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-Bromo-5-(4-fluorophenylethynyl)-pyridine | HCID 67047615 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 3-Bromo-5-(4-fluorophenylethynyl)-pyridine hydrochloride | HCID 67047763 | — |
Reaction Steps
Add 1 M hydrogen chloride in diethyl ether (1.1 eq) to 3-bromo-5-(4-fluorophenylethynyl)-pyridine, from PREPARATION 24, in diethyl ether and stir for 2 h. Filter and dry the collected solid under high vacuum to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915424B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-1a0de6886ecf4be6a0bcda3e56eff07e |
| Source note | uspto-grants-2011_03 |