Potassium Carbonate → 1-(5-Phenylethynyl-pyridin-3-yl)-ethanone oxime hydrochloride

Participants

Reaction Steps

Prepared in the same manner as described in EXAMPLE 6, using 1-(5-phenylethynyl-pyridin-3-yl)-ethanone, (prepared as described in EXAMPLE 166), (0.22 g, 0.97 mmol), hydroxylamine hydrochloride (0.54 g, 7.78 mmol) and potassium carbonate (0.67 g, 4.86 mmol) to give the free base of the title compound. Convert the free base to the hydrochloride salt as described in EXAMPLE 163 to give the title compound (0.112 g, 42%).

Provenance & Evidence