4-Chloro-3-nitrophenol → HCID 60204761, compound

HRID 607173Notes

Reaction equation

HRID 607173 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].Br[CH2:13][C:14]1[CH:21]=[CH:20][C:17]([C:18]#[N:19])=[CH:16][CH:15]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:13][C:14]2[CH:21]=[CH:20][C:17]([C:18]#[N:19])=[CH:16][CH:15]=2)=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10]

Participants

3

Reactant 2

HCID 691274-Chloro-3-nitrophenolHCID 869964-(Bromomethyl)benzonitrile

Product 1

HCID 60204761HCID 60204761, compound

Procedure

A solution of 4-chloro-3-nitro-phenol was reacted with 4-Bromomethyl-benzonitrile using the conditions described in Example 10C to provide 4-(4-Chloro-3-nitro-phenoxymethyl)-benzonitrile which was treated sequentially using the procedures from Examples 10D and 10E to provide the title product.

Sources & evidence

ORD record
ord-9ac08b802343429b9deb371454af1370
Source dataset
uspto-grants-2011_03
Patent number
US07915411B2

Reaction notes

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