Boron tribromide → HCID 66808558, compound

HRID 607281Notes

Reaction equation

HRID 607281 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([S:9][C:10]2[CH:11]=[C:12]([NH2:17])[CH:13]=[C:14]([CH3:16])[CH:15]=2)=[CH:5][CH:4]=1.B(Br)(Br)Br>ClCCl>[NH2:17][C:12]1[CH:11]=[C:10]([S:9][C:6]2[CH:7]=[CH:8][C:3]([OH:2])=[CH:4][CH:5]=2)[CH:15]=[C:14]([CH3:16])[CH:13]=1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 66808444HCID 66808444, compound

Product 1

HCID 66808558HCID 66808558, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To the product from Example 181B (0.5 g, 2.0 mmol) in dichloromethane was treated with boron tribromide (10 mmol) at room temperature for 1 hour. The solution was the extracted with water, then the organic solution dried and concentrated to provide the title compound.

Workup

  1. extractionextracted with water
  2. customthe organic solution dried
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-38509a7750704952b1ee54cbdca2e7fd
Source dataset
uspto-grants-2011_03
Patent number
US07915411B2

Reaction notes

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