HCID 66808620, compound → HCID 57667805, compound

HRID 607325Notes

Reaction equation

HRID 607325 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:4][C:3]=1[N+:16]([O-])=O.[H][H]>[Pd].C(O)C>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)=[CH:4][C:3]=1[NH2:16]

Participants

5

Reactant 2

HCID 66808620HCID 66808620, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 57667805HCID 57667805, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of the product from Example 241A (0.166 g, 0.694 mmol) and 10% palladium on charcoal (18.4 mg, 0.025 eq), in ethanol (10 mL) was stirred under one atmosphere of hydrogen for 16 hours. The reaction mixture was then filtered through Celite and the solvent evaporated under reduced pressure to provide the title compound as a slightly red oil (0.141 g, 96% yield).

Workup

  1. filtrationThe reaction mixture was then filtered through Celite
  2. customthe solvent evaporated under reduced pressure

Sources & evidence

ORD record
ord-46a00a0a139840c593a7a730ab3a2cdb
Source dataset
uspto-grants-2011_03
Patent number
US07915411B2

Reaction notes

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