HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl{3-[s-methyl-n-(trifluoroacetyl)sulfonimidoyl]phenyl}acetate → methyl {3-[N-({6-amino-5-[(3-{[(1,3-dimethyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)ethynyl]pyridin-3-yl}carbonyl)-S-methylsulfonimidoyl]phenyl}acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl{3-[s-methyl-n-(trifluoroacetyl)sulfonimidoyl]phenyl}acetate | HCID 57657827 | — |
| Reactant | 6-Amino-5-{3-[(2,5-dimethyl-2H-pyrazole-3-carbonyl)-amino]-phenylethynyl}-nicotinic acid | HCID 57657867 | — |
| Product | methyl {3-[N-({6-amino-5-[(3-{[(1,3-dimethyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)ethynyl]pyridin-3-yl}carbonyl)-S-methylsulfonimidoyl]phenyl}acetate | HCID 57657942 | — |
Reaction Steps
In a manner similar to that described in Example 496 (step 5), 6-amino-5-[(3-{[(1,3-dimethyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)ethynyl]nicotinic acid and methyl{3-[S-methyl-N-(trifluoroacetyl)sulfonimidoyl]phenyl}acetate were reacted to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07915443B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-55ebc3c95f764e4389a17fa510678c18 |
| Source note | uspto-grants-2011_03 |