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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 60825Generated: October 29, 2026

5-(3-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid → Methyl 1-(5-(3-fluorophenyl)-2-methylthiazole-4-carbonyl)-5,5-dimethoxypiperidine-2-carboxylate

https://huagongshe.com/reaction/60825

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(3-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acidHCID 57437174—
ReactantMethyl 5,5-dimethoxypiperidine-2-carboxylateHCID 89739337—
ProductMethyl 1-(5-(3-fluorophenyl)-2-methylthiazole-4-carbonyl)-5,5-dimethoxypiperidine-2-carboxylateHCID 89739507—

Reaction Steps

Methyl 1-(5-(3-fluorophenyl)-2-methylthiazole-4-carbonyl)-5,5-dimethoxypiperidine-2-carboxylate was prepared according to general procedure A using product methyl 5,5-dimethoxypiperidine-2-carboxylate and 5-(3-fluorophenyl)-2-methylthiazole-4-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-2450f20f22a4490f8cb23fc37cf78f8b
Source noteuspto-grants-2016_09