Phthalimide → HCID 89739501, compound

HRID 60827Notes

Reaction equation

[F:1][C:2]1[CH:3]=[C:4]([C:8]2[S:12][C:11]([CH3:13])=[N:10][C:9]=2[C:14]([N:16]2[CH2:21][CH:20]([O:22][CH3:23])[CH2:19][CH2:18][CH:17]2[CH2:24]O)=[O:15])[CH:5]=[CH:6][CH:7]=1.[C:26]1(=[O:36])[NH:30][C:29](=[O:31])[C:28]2=[CH:32][CH:33]=[CH:34][CH:35]=[C:27]12>>[F:1][C:2]1[CH:3]=[C:4]([C:8]2[S:12][C:11]([CH3:13])=[N:10][C:9]=2[C:14]([N:16]2[CH2:21][CH:20]([O:22][CH3:23])[CH2:19][CH2:18][CH:17]2[CH2:24][N:30]2[C:26](=[O:36])[C:27]3[C:28](=[CH:32][CH:33]=[CH:34][CH:35]=3)[C:29]2=[O:31])=[O:15])[CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 6809Phthalimide

HCID 89739794HCID 89739794, compound

Product 1

HCID 89739501HCID 89739501, compound

Procedure

2-((1-(5-(3-Fluorophenyl)-2-methylthiazole-4-carbonyl)-5-methoxypiperidin-2-yl)methyl)isoindoline-1,3-dione was prepared according to general procedure I using (5-(3-fluorophenyl)-2-methylthiazol-4-yl)(2-(hydroxymethyl)-5-methoxypiperidin-1-yl)methanone and phthalimide.

Sources & evidence

ORD record: ord-1c411b2b4a754f9eb9046a8e2beb7222
Source dataset: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09440982B2

Reaction notes

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